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Search Results for " lag 3 "

13

抑制剂 & 化合物

83

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T78266	Anti-Mouse LAG-3 Antibody (C9B7W)
	Anti-MouseLAG-3Antibody为针对小鼠LAG-3的Rat源IgG1抗体抑制剂。
T9901A-001	Relatlimab BMS-986016	Others	Others
	Relatlimab(BMS-986016) 是一种靶向人抗 LAG-3 的单克隆抗体，由携带重组 LAG-3 蛋白的人免疫球蛋白的转基因小鼠免疫生成。Relatlimb 有阻断作用，可阻断 LAG-3/MHC II 的相互作用（IC50 ： 0.67 nM），阻断了 LAG-3/FGL1 的相互作用（ IC50：0.019 nM）。Relatlimab 常与 Nivoluma 一起用来治疗晚期黑色素瘤。
T76985	Tebotelimab
	Tebotelimab (MGD-013) 是一种人源的 IgG4κ 双特异性 PD-1/LAG-3双亲和再靶向 (DART) 抗体。Tebotelimab 结合 NS0 细胞表面表达的 PD-1和 LAG-3，EC50分别为 1.65 nM 和 0.41 nM。Tebotelimab 阻断 PD-1/PD-L1、PD-1/PD-L2 和 LAG-3/HLA (MHC-II) 相互作用和 PD-1信号。Tebotelimab 可恢复耗尽的 T 细胞功能并增强抗肿瘤免疫力。
T81790	Miptenalimab BI-754111
	Miptenalimab (BI-754111)为一种高亲和力抗人LAG-3抗体，其对hLAG-3的结合常数(KD)为88.6 nM。该抗体能有效阻断LAG-3与其主要配体MHC-II之间的相互作用。
T68322	IMP-321
	IMP-321 is a soluble dimeric recombinant form of LAG-3 and first-in-class antigen presenting cell activator.
T76859	Bavunalimab
	Bavunalimab（Anti-Human CTLA4xLAG3）为一种针对CTLA-4/LAG-3的双特异性人源化单克隆抗体。该化合物通过激活NSG小鼠中的T细胞，可用于癌症研究。
T82414	Favezelimab MK-4280
	Favezelimab（MK-4280）为人源化抗LAG-3单克隆抗体，能够抑制LAG-3与其配体MHC II类结合。该抗体联合PD-L1抑制剂Pembrolizumab在结直肠癌（CRC）治疗研究中展现出应用前景。
T78247	Ieramilimab IMP701,LAG525
	Ieramilimab（LAG525；IMP701）是一款针对LAG-3的人源化IgG4单克隆抗体，它通过结合到LAG-3来阻断其与MHC-II 分子的相互作用。
T78314	Fianlimab REGN3767
	Fianlimab（REGN3767）为一种靶向T细胞免疫检查点受体LAG-3的人源单克隆抗体，展现出抗肿瘤活性。
T80918	Tuparstobart Incagn-02385
	Tuparstobart (Incagn-02385)为针对LAG-3的IgG1κ抗体。LAG-3，作为一种免疫检查点受体蛋白，其主要存在于活化T细胞、NK细胞、B细胞及浆细胞树突细胞上。
T78293	TSR-033
	TSR-033为针对LAG-3（淋巴细胞活化基因-3）的人源化IgG4高亲和力抗体，能增强T细胞功能及PD-1阻断效果，适用于体外及体内。作为与T细胞功能障碍相关的共抑制受体，LAG-3常与PD-1共同表达，TSR-033因此表现出抗肿瘤活性。
T82471	Encelimab
	Encelimab是一种抗LAG3抗体，能够阻断 LAG-3 与 MHC II 的交互作用并增强T细胞活性。在单独应用或与抗PD-1抗体结合时，Encelimab能有效减小A20细胞异种移植瘤小鼠模型中的淋巴瘤肿瘤体积。
T72626	A2AR-antagonist-1	Adenosine Receptor	GPCR/G Protein; Neuroscience
	A2AR-antagonist-1 (compound 38) 为一种口服活性的腺苷 A2A 受体 (A2AR) 拮抗剂，IC50 值为 29 nM。此化合物展示出抗肿瘤作用，并在小鼠肝微粒体中表现出良好的代谢稳定性，半衰期为 86.1 分钟。同时，A2AR-antagonist-1 能够作为 T 细胞激活剂，通过抑制免疫抑制分子 LAG-3 和 TIM-3，以及增强 GZMB、IFNG 和 IL-2 等效应分子的表达。

化合物

Anti-Mouse LAG-3 Antibody (C9B7W)

Cat.No: T78266

Cat.No: T9901A-001

Synonym: BMS-986016

Target: Others

Cat.No: T76985

Cat.No: T81790

Synonym: BI-754111

Cat.No: T68322

Cat.No: T76859

Cat.No: T82414

Synonym: MK-4280

Cat.No: T78247

Synonym: IMP701,LAG525

Cat.No: T78314

Synonym: REGN3767

Cat.No: T80918

Synonym: Incagn-02385

Cat.No: T78293

Cat.No: T82471

A2AR-antagonist-1

Cat.No: T72626

Target: Adenosine Receptor

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04939	LAG-3 Protein, Human, Recombinant LAG-3,lymphocyte-activation gene 3	Human	HEK293 Cells
	LAG-3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.3 kDa and the accession number is P18627-1.
TMPY-04730	LAG-3 Protein, Human, Recombinant (His) LAG-3,lymphocyte-activation gene 3	Human	HEK293 Cells
	LAG-3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.6 kDa and the accession number is P18627-1.
TMPY-04731	LAG-3 Protein, Human, Recombinant (mFc) lymphocyte-activation gene 3,CD223,LAG...	Human	HEK293 Cells
	LAG-3 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 72.6 kDa and the accession number is P18627-1.
TMPY-05746	LAG-3 Protein, Mouse, Recombinant lymphocyte-activation gene 3,LAG-3	Mouse	HEK293 Cells
	LAG-3 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.25 kDa and the accession number is Q61790.
TMPY-04528	LAG-3 Protein, Human, Recombinant (hFc) lymphocyte-activation gene 3,CD223,LAG...	Human	HEK293 Cells
	LAG-3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 72.9 kDa and the accession number is P18627-1.
TMPY-04612	LAG-3 Protein, Mouse, Recombinant (His) LAG-3,Ly66,lymphocyte-activation gene ...	Mouse	HEK293 Cells
	LAG-3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.7 kDa and the accession number is Q61790.
TMPY-05130	LAG-3 Protein, Human, Recombinant, Biotinylated lymphocyte-activation gene 3,CD223,LAG...	Human	HEK293 Cells
	LAG-3 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.3 kDa and the accession number is P18627-1.
TMPY-04611	LAG-3 Protein, Mouse, Recombinant (hFc) lymphocyte-activation gene 3,Ly66,LAG-...	Mouse	HEK293 Cells
	LAG-3 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 72.1 kDa and the accession number is Q61790.
TMPY-06931	LAG-3 Protein, Human, Recombinant (hFc & Avi), Biotinylated lymphocyte-activation gene 3,CD223,LAG...	Human	HEK293 Cells
	LAG-3 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 74.73 kDa and the accession number is NP_002277.4.
TMPJ-01421	LAG-3 Protein, Cynomolgus, Recombinant (hFc) LAG-3,Protein FDC,Lymphocyte activation ge...	Cynomolgus	HEK293 Cells
	LAG-3 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90 KDa and the accession number is XP_005570011.1.
TMPJ-00321	LAG-3 Protein, Human, Recombinant (His & Avi), Biotinylated Lymphocyte activation gene 3 protein,CD223...	Human	HEK293 Cells
	LAG-3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 60-70 KDa and the accession number is P18627.
TMPY-05092	LAG-3 Protein, Cynomolgus, Recombinant (74 Pro, His) lymphocyte-activation gene 3	Cynomolgus	HEK293 Cells
	LAG-3 Protein, Cynomolgus, Recombinant (74 Pro, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.4 kDa and the accession number is XP_005570011.1.
TMPY-03759	LAG-3 Protein, Rat, Recombinant (His) lymphocyte-activation gene 3	Rat	HEK293 Cells
	LAG-3 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.1 kDa and the accession number is Q5BK54.
TMPK-00640	DLL3 Protein, Rhesus macaque, Recombinant (His) SCDO1delta3,Pudgy,δ3,SCDO1,SCDO1δ3	Rhesus	HEK293 Cells
	Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 51 kDa and t...
TMPK-00543	DLL3 Protein, Cynomolgus, Recombinant (aa 27-477, His) DLL3,SCDO1δ3,SCDO1,Pudgy,Delta3,δ...	Cynomolgus	HEK293 Cells
	Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein, Cynomolgus, Recombinant (aa 27-477, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 48.80...
TMPK-01206	DLL3 Protein, Human, Recombinant (His & Avi) DLL3,Pudgy,Delta3,δ3,SCDO1delta	Human	HEK293 Cells
	Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 21.20 kDa a...
TMPK-00748	DLL3 Protein, Mouse, Recombinant (His) Delta3,Pudgy,SCDO1δ3,DLL3,δ3<...	Mouse	HEK293 Cells
	Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 49.02 kDa and the acc...
TMPK-01207	DLL3 Protein, Human, Recombinant (His & Avi), Biotinylated Pudgy,δ3,SCDO1δ3,Delta3,SCDO1delt...	Human	HEK293 Cells
	Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight ...
TMPK-00204	FGL1 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated Hepassocin,Lag3 ligand,HP-041,LFIRE-1,HFRE...	Human	HEK293 Cells
	Fibrinogen-like protein 1 (FGL-1) is a protein that is structurally related to fibrinogen. In humans, FLG-1 is encoded by the FGL1 gene.Fibrinogen-like protein 1 is a member of the fibrinogen family of proteins, which also includes fibrinogen, fibrinogen-like protein 2, and clotting factors V, VIII, and XIII.Fibrinogen-like Protein 1 is a major immune inhibitory ligand of LAG-3.
TMPK-01208	DLL3 Protein, Human, Recombinant (His & Flag) Pudgy,SCDO1,DLL3,Delta3,SCDO1δ3,δ...	Human	HEK293 Cells
	Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-His-Flag tag. The predicted molecular weight is 22.30 kDa...
TMPK-01209	DLL3 Protein, Human, Recombinant (His) Pudgy,SCDO1delta3,DLL3,SCDO1δ3,SC...	Human	HEK293 Cells
	Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 50.4 kDa and the acce...
TMPK-01210	DLL3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated DLL3,SCDO1δ3,SCDO1,Pudgy,δ3,SCDO1...	Human	HEK293 Cells
	Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with N-His tag. The predicted mo...
TMPK-00542	DLL3 Protein, Cynomolgus, Recombinant (aa 27-488, His) SCDO1,Delta3,SCDO1δ3,δ3,SCDO1delt...	Cynomolgus	HEK293 Cells
	Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein, Cynomolgus, Recombinant (aa 27-488, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 49.21...
TMPJ-00197	FGL1 Protein, Human, Recombinant (hFc & Avi), Biotinylated FGL1,HP-041,Fibrinogen-like protein 1,LFIRE-1,Hepassocin,HFR...	Human	HEK293 Cells
	Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major imm...
TMPY-06986	FGF-8b Protein, Human, Recombinant NEWENTRY,fibroblast growth factor 8 (androgen-induced),FGF-8...	Human	E. coli
	In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling fac...
TMPY-00132	Mesothelin Protein, Human, Recombinant MPF,SMRP,Mesothelin	Human	HEK293 Cells
	Mesothelin Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 32.4 kDa and the accession number is Q13421-3.
TMPY-04935	CD47 Protein, Human, Recombinant (aa 1-139, His) MER6,CD47 molecule,IAP,OA3	Human	HEK293 Cells
	CD47 Protein, Human, Recombinant (aa 1-139, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is Q08722-3.
TMPY-03763	Neuropilin-2 Protein, Human, Recombinant (hFc) Neuropilin-2,NPN2,neuropilin 2,PRO2714,VEGF165R2,NP2	Human	HEK293 Cells
	Neuropilin-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 120.7 kDa and the accession number is O60462-3.
TMPY-05191	CD47 Protein, Human, Recombinant, Biotinylated CD47 molecule,MER6,OA3,IAP	Human	HEK293 Cells
	CD47 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.
TMPY-04683	CD47 Protein, Human, Recombinant MER6,CD47 molecule,OA3,IAP	Human	HEK293 Cells
	CD47 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.
TMPY-00072	GITR/TNFRSF18 Protein, Human, Recombinant (His) AITR,GITR-D,tumor necrosis factor receptor superfamily, memb...	Human	HEK293 Cells
	GITR/TNFRSF18 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16 kDa and the accession number is Q9Y5U5-3.
TMPY-01020	Periostin/OSF-2 Protein, Human, Recombinant (His) PN,OSF-2,OSF2,periostin,periostin, osteoblast specific facto...	Human	HEK293 Cells
	Periostin/OSF-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.4 kDa and the accession number is Q15063-3.
TMPY-00892	Neuropilin-2 Protein, Human, Recombinant (His) NP2,PRO2714,VEGF165R2,neuropilin 2,NPN2,Neuropilin-2	Human	HEK293 Cells
	Neuropilin-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 95 kDa and the accession number is O60462-3.
TMPY-01897	PRSS3 Protein, Human, Recombinant (His) PRSS4,TRY4,TRY3,RP11-176F3.3,T9,M...	Human	HEK293 Cells
	Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains one peptidase S1 domain. Trypsin-3 / PRSS3 can degrade intrapancreatic trypsin inhibitors that protect against CP. Genetic variants that cause higher mesotrypsin activity might increase the risk for chronic pancreatitis (CP). A sustained imbalance of pancreatic proteases and their ...
TMPY-05748	CD45 Protein, Human, Recombinant (aa 26-577, His) L-CA,T200,LCA,B220,protein tyrosine phosphatase, receptor ty...	Human	HEK293 Cells
	CD45 Protein, Human, Recombinant (aa 26-577, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62.2 kDa and the accession number is P08575-3.
TMPY-04142	RANK/TNFRSF11A Protein, Human, Recombinant (hFc) OPTB7,OFE,OSTS,LOH18CR1,FEO,TRANCER,tumor necrosis factor re...	Human	HEK293 Cells
	RANK/TNFRSF11A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.8 kDa and the accession number is Q9Y6Q6-3.
TMPJ-01099	IL-15RA Protein, Human, Recombinant (hFc, Human Cells) interleukin-15 receptor subunit α,IL15RA,interleukin-15 rece...	Human	HEK293 Cells
	Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and “transpresent” cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Rα can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15Rα complexes exhibit a strong agonistic activity which is mediated through membrane-boun...
TMPY-01180	CD86 Protein, Human, Recombinant (His) CD86 antigen,B70,B7.2,B7-2,CD28LG2,LAB72	Human	HEK293 Cells
	CD86 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is P42081-3.
TMPY-04298	CDCP1 Protein, Human, Recombinant (His) TRASK,CD318,CUB domain containing protein 1,SIMA1	Human	HEK293 Cells
	CDCP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.4 kDa and the accession number is Q9H5V8-3.
TMPY-00357	HNT/NTM Protein, Human, Recombinant (His) HNT,NTRI,IGLON2,neurotrimin	Human	HEK293 Cells
	HNT/NTM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.3 kDa and the accession number is Q9P121-3.
TMPY-00480	NCAM1 Protein, Human, Recombinant (His) neural cell adhesion molecule 1,CD56,MSK39,NCAM	Human	HEK293 Cells
	NCAM1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 66.1 kDa and the accession number is P13591-3.
TMPK-00447	CD45 Protein, Human, Recombinant (aa 26-577, hFc) CD45,CD45R,LCA,PTPRC,L-CA,T200,B220,GP180,LY5,EC 3....	Human	HEK293 Cells
	PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts. CD45 Protein, Human, Recombinant (aa 26-577...
TMPY-03621	EphB2 Protein, Mouse, Recombinant (hFc) Tyro5,Erk,Qek5,ETECK,Hek5,Drt,EPH receptor B2,Nuk,Prkm5,Sek<...	Mouse	HEK293 Cells
	EphB2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84.6 kDa and the accession number is P54763-3.
TMPJ-01288	KLF6 Protein, Human, Recombinant CPBP,GC-Rich Sites-Binding Factor GBF,Suppressor of Tumorige...	Human	E. coli
	Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by spleen, thymus, prostate, testis, small intestinem and colon. However, it is weakly expressed in the pancreas, lung, liver, heart, and skeletal muscle. KLF6 functions as a transcriptional activator and could play a role in B-cell growth and development. Defects in KLF6 will resul...
TMPY-04386	EphB2 Protein, Human, Recombinant (aa 570-987, His & GST) PCBC,CAPB,Hek5,EK5,EPHT3,EPH receptor B2,Tyro5,DRT,...	Human	Baculovirus Insect Cells
	EphB2 Protein, Human, Recombinant (aa 570-987, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75.2 kDa and the accession number is P29323-3.
TMPY-01268	SMYD3 Protein, Human, Recombinant (GST) SET and MYND domain containing 3,ZMYND1,KMT3	Human	Baculovirus Insect Cells
	SET and MYND domain-containing protein 3, also known as Zinc finger MYND domain-containing protein 1, SMYD3, and ZMYND, is a member of the histone-lysine methyltransferase family. SMYD3 contains one MYND-type zinc finger and one SET domain. SMYD3 is a histone H3 lysine-4-specific methyltransferase. It is expressed in skeletal muscles and testis. It is overexpressed in a majority of colorectal carcinoma (CRC) and hepatocellular carcinoma (HCC). SMYD3 plays an important role in transcriptional reg...
TMPY-03149	CDCP1 Protein, Human, Recombinant (mFc) TRASK,SIMA135,CD318,CUB domain containing ...	Human	HEK293 Cells
	CDCP1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 61.4 kDa and the accession number is Q9H5V8-3.
TMPK-00401	FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated ECT1,K-SAM,CD332,CEK3,FGFR2 α,CFD...	Human	HEK293 Cells
	Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs.
TMPK-00398	FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi) Fibroblast growth factor receptor 2,CD332,...	Human	HEK293 Cells
	FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi) is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and the accession number is P21802-3.
TMPJ-00391	FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc) FGF R2b,KGFR,BFR-1,FGFR2 β,FGFR2b,FGFR2,FGFR2 beta,CD3	Human	HEK293 Cells
	FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 85-120 KDa and the accession number is P21802-3.
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重组蛋白

LAG-3 Protein, Human, Recombinant

Cat.No: TMPY-04939

Species: Human

Expression System: HEK293 Cells

LAG-3 Protein, Human, Recombinant (His)

Cat.No: TMPY-04730

Species: Human

Expression System: HEK293 Cells

LAG-3 Protein, Human, Recombinant (mFc)

Cat.No: TMPY-04731

Species: Human

Expression System: HEK293 Cells

LAG-3 Protein, Mouse, Recombinant

Cat.No: TMPY-05746

Species: Mouse

Expression System: HEK293 Cells

LAG-3 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04528

Species: Human

Expression System: HEK293 Cells

LAG-3 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04612

Species: Mouse

Expression System: HEK293 Cells

LAG-3 Protein, Human, Recombinant, Biotinylated

Cat.No: TMPY-05130

Species: Human

Expression System: HEK293 Cells

LAG-3 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-04611

Species: Mouse

Expression System: HEK293 Cells

LAG-3 Protein, Human, Recombinant (hFc & Avi), Biotinylated

Cat.No: TMPY-06931

Species: Human

Expression System: HEK293 Cells

LAG-3 Protein, Cynomolgus, Recombinant (hFc)

Cat.No: TMPJ-01421

Species: Cynomolgus

Expression System: HEK293 Cells

LAG-3 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPJ-00321

Species: Human

Expression System: HEK293 Cells

LAG-3 Protein, Cynomolgus, Recombinant (74 Pro, His)

Cat.No: TMPY-05092

Species: Cynomolgus

Expression System: HEK293 Cells

LAG-3 Protein, Rat, Recombinant (His)

Cat.No: TMPY-03759

Species: Rat

Expression System: HEK293 Cells

DLL3 Protein, Rhesus macaque, Recombinant (His)

Cat.No: TMPK-00640

Species: Rhesus

Expression System: HEK293 Cells

DLL3 Protein, Cynomolgus, Recombinant (aa 27-477, His)

Cat.No: TMPK-00543

Species: Cynomolgus

Expression System: HEK293 Cells

DLL3 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-01206

Species: Human

Expression System: HEK293 Cells

DLL3 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00748

Species: Mouse

Expression System: HEK293 Cells

DLL3 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-01207

Species: Human

Expression System: HEK293 Cells

FGL1 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated

Cat.No: TMPK-00204

Species: Human

Expression System: HEK293 Cells

DLL3 Protein, Human, Recombinant (His & Flag)

Cat.No: TMPK-01208

Species: Human

Expression System: HEK293 Cells

DLL3 Protein, Human, Recombinant (His)

Cat.No: TMPK-01209

Species: Human

Expression System: HEK293 Cells

DLL3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated

Cat.No: TMPK-01210

Species: Human

Expression System: HEK293 Cells

DLL3 Protein, Cynomolgus, Recombinant (aa 27-488, His)

Cat.No: TMPK-00542

Species: Cynomolgus

Expression System: HEK293 Cells

FGL1 Protein, Human, Recombinant (hFc & Avi), Biotinylated

Cat.No: TMPJ-00197

Species: Human

Expression System: HEK293 Cells

FGF-8b Protein, Human, Recombinant

Cat.No: TMPY-06986

Species: Human

Expression System: E. coli

Mesothelin Protein, Human, Recombinant

Cat.No: TMPY-00132

Species: Human

Expression System: HEK293 Cells

CD47 Protein, Human, Recombinant (aa 1-139, His)

Cat.No: TMPY-04935

Species: Human

Expression System: HEK293 Cells

Neuropilin-2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-03763

Species: Human

Expression System: HEK293 Cells

CD47 Protein, Human, Recombinant, Biotinylated

Cat.No: TMPY-05191

Species: Human

Expression System: HEK293 Cells

CD47 Protein, Human, Recombinant

Cat.No: TMPY-04683

Species: Human

Expression System: HEK293 Cells

GITR/TNFRSF18 Protein, Human, Recombinant (His)

Cat.No: TMPY-00072

Species: Human

Expression System: HEK293 Cells

Periostin/OSF-2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01020

Species: Human

Expression System: HEK293 Cells

Neuropilin-2 Protein, Human, Recombinant (His)

Cat.No: TMPY-00892

Species: Human

Expression System: HEK293 Cells

PRSS3 Protein, Human, Recombinant (His)

Cat.No: TMPY-01897

Species: Human

Expression System: HEK293 Cells

CD45 Protein, Human, Recombinant (aa 26-577, His)

Cat.No: TMPY-05748

Species: Human

Expression System: HEK293 Cells

RANK/TNFRSF11A Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04142

Species: Human

Expression System: HEK293 Cells

IL-15RA Protein, Human, Recombinant (hFc, Human Cells)

Cat.No: TMPJ-01099

Species: Human

Expression System: HEK293 Cells

CD86 Protein, Human, Recombinant (His)

Cat.No: TMPY-01180

Species: Human

Expression System: HEK293 Cells

CDCP1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04298

Species: Human

Expression System: HEK293 Cells

HNT/NTM Protein, Human, Recombinant (His)

Cat.No: TMPY-00357

Species: Human

Expression System: HEK293 Cells

NCAM1 Protein, Human, Recombinant (His)

Cat.No: TMPY-00480

Species: Human

Expression System: HEK293 Cells

CD45 Protein, Human, Recombinant (aa 26-577, hFc)

Cat.No: TMPK-00447

Species: Human

Expression System: HEK293 Cells

EphB2 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-03621

Species: Mouse

Expression System: HEK293 Cells

KLF6 Protein, Human, Recombinant

Cat.No: TMPJ-01288

Species: Human

Expression System: E. coli

EphB2 Protein, Human, Recombinant (aa 570-987, His & GST)

Cat.No: TMPY-04386

Species: Human

Expression System: Baculovirus Insect Cells

SMYD3 Protein, Human, Recombinant (GST)

Cat.No: TMPY-01268

Species: Human

Expression System: Baculovirus Insect Cells

CDCP1 Protein, Human, Recombinant (mFc)

Cat.No: TMPY-03149

Species: Human

Expression System: HEK293 Cells

FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00401

Species: Human

Expression System: HEK293 Cells

FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi)

Cat.No: TMPK-00398

Species: Human

Expression System: HEK293 Cells

FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc)

Cat.No: TMPJ-00391

Species: Human

Expression System: HEK293 Cells

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